damaged cells Hips With Mother's Help director
Tuesday, April 13, 2010
Tranny Wearing Tampons
Bone stem cells the future could be used instead of donor bone as part of an innovative new treatment for hip replacement, according to scientists at the University of Southampton.
A team from the University School of Medicine believe that the introduction of a patient's own cells madre del esqueleto en la articulación de la cadera durante el injerto óseo se re-crecimiento más éxito y reparación.
La técnica del injerto se utiliza para reparar el hueso del muslo y la articulación durante el reemplazo (conocido como «revisión») la terapia de reemplazo de cadera, un procedimiento en el que los cirujanos introducen ósea del donante a la zona dañada para proporcionar apoyo a la madre nueva cadera.
En este estudio de colaboración entre la Universidad de Southampton y la Universidad de Nottingham, los investigadores used adult stem cells from bone marrow, combined with innovative retention process and polymer scaffolds.
In a two-year study, funded by the Medical Research Council (MRC), the researchers aim to improve the outcome of this procedure with high impact.
"Surgeons now use donor bone for bone grafting, so the introduction of own patient's stem cells to create a living cell or composite material would to an entirely new approach, "says Professor Richard Oreffo, an expert in musculoskeletal science at the University of Southampton, who heads the project.
"This is very much the beginning of a project to investigate the potential of this new technique, but our preliminary work suggests that this may have important therapeutic implications."
When a joint the hip is damaged, the part of the thigh bone or femur, including the ball, can be removed and a new artificial joint to the bone remaining thigh. Revision hip replacement occurs when that artificial joint needs to change. Professor
Oreffo introduce the stem cells for the hip joint using a scaffold or support structure that is designed to protect them, and impaction process again.
polymer scaffolds will be developed by Professors Steve Howdle and Kevin Shakesheff, experts in chemistry and tissue engineering at the University of Nottingham.
Professor Howdle said: "On the basis of strong partnerships with experts in tissue engineering, this new grant will allow researchers to make their materials Nottingham closer to the clinic.
"This could have major benefits for patients, and also offer significant cost savings to health authorities, but first we need to verify and are based on our preliminary data."
"An important part of work in Nottingham will involve the extension of equipment supercritical fluid processing para crear más grandes y más lotes homogéneos de polímero andamios para la prueba."
El Dr. Chris Watkins, Traducción MRC Líder temático, dice: "Resiliencia, reparación y reemplazo es un área de investigación prioritaria en el plan estratégico de la MRC, 'Vidas Los cambios de Investigación. Este estudio pone de manifiesto cómo un enfoque regenerativo puede ofrecer una esperanza real para hacer frente a un problema importante para una población que envejece. "
Estos permitirána fund groups based on initial studies showing that the degradable polymer scaffolds prepared using technology of supercritical carbon dioxide can have a dramatic effect on surgical procedures such as the insertion of a hip implant in revision hip surgery.
interim studies conducted in Southampton shows that the polymers can contribute to bone formation through the creation of a living cell / composite material and bonding assistance of hip implants.
A team from the University School of Medicine believe that the introduction of a patient's own cells madre del esqueleto en la articulación de la cadera durante el injerto óseo se re-crecimiento más éxito y reparación.
La técnica del injerto se utiliza para reparar el hueso del muslo y la articulación durante el reemplazo (conocido como «revisión») la terapia de reemplazo de cadera, un procedimiento en el que los cirujanos introducen ósea del donante a la zona dañada para proporcionar apoyo a la madre nueva cadera.
En este estudio de colaboración entre la Universidad de Southampton y la Universidad de Nottingham, los investigadores used adult stem cells from bone marrow, combined with innovative retention process and polymer scaffolds.
In a two-year study, funded by the Medical Research Council (MRC), the researchers aim to improve the outcome of this procedure with high impact.
"Surgeons now use donor bone for bone grafting, so the introduction of own patient's stem cells to create a living cell or composite material would to an entirely new approach, "says Professor Richard Oreffo, an expert in musculoskeletal science at the University of Southampton, who heads the project.
"This is very much the beginning of a project to investigate the potential of this new technique, but our preliminary work suggests that this may have important therapeutic implications."
When a joint the hip is damaged, the part of the thigh bone or femur, including the ball, can be removed and a new artificial joint to the bone remaining thigh. Revision hip replacement occurs when that artificial joint needs to change. Professor
Oreffo introduce the stem cells for the hip joint using a scaffold or support structure that is designed to protect them, and impaction process again.
polymer scaffolds will be developed by Professors Steve Howdle and Kevin Shakesheff, experts in chemistry and tissue engineering at the University of Nottingham.
Professor Howdle said: "On the basis of strong partnerships with experts in tissue engineering, this new grant will allow researchers to make their materials Nottingham closer to the clinic.
"This could have major benefits for patients, and also offer significant cost savings to health authorities, but first we need to verify and are based on our preliminary data."
"An important part of work in Nottingham will involve the extension of equipment supercritical fluid processing para crear más grandes y más lotes homogéneos de polímero andamios para la prueba."
El Dr. Chris Watkins, Traducción MRC Líder temático, dice: "Resiliencia, reparación y reemplazo es un área de investigación prioritaria en el plan estratégico de la MRC, 'Vidas Los cambios de Investigación. Este estudio pone de manifiesto cómo un enfoque regenerativo puede ofrecer una esperanza real para hacer frente a un problema importante para una población que envejece. "
Estos permitirána fund groups based on initial studies showing that the degradable polymer scaffolds prepared using technology of supercritical carbon dioxide can have a dramatic effect on surgical procedures such as the insertion of a hip implant in revision hip surgery.
interim studies conducted in Southampton shows that the polymers can contribute to bone formation through the creation of a living cell / composite material and bonding assistance of hip implants.
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